A link between DNA methylation and epigenetic silencing in transgenic Volvox carteri

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A link between DNA methylation and epigenetic silencing in transgenic Volvox carteri.

Epigenetic silencing of foreign genes introduced into plants poses an unsolved problem for transgenic technology. Here we have used the simple multicellular green alga VOLVOX: carteri as a model to analyse the relation of DNA methylation to transgenic silencing. VOLVOX: DNA contains on average 1.1% 5-methylcytosine and 0.3% N6-methyladenine, as revealed by electrospray mass spectrometry and pho...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2001

ISSN: 1362-4962

DOI: 10.1093/nar/29.6.1261